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    امروز  سه شنبه - ۶ فروردین - ۱۳۹۸  

Multiphoton fluorescence microscopy, in which a fluorophore absorbs more than one photon and emits light at a shorter wavelength than the excitation source, can be used to create 3D tissue images at depths of 1 mm or more. Recently, studies have shown that in vivo two- and three-photon microscopy can image neurons and vascular structures beyond the cortex in the brains of mice. Imaging the vasculature requires intravenous injection of contrast agents that absorb strongly in the near-infrared and have prolonged blood circulation times. Traditionally, organic dyes are used, despite their poor photostability and low quantum yields. Quantum dots represent a brighter, more stable class of contrast agent, but they introduce substantial toxicity ...

Research team develops material to separate oil and water for environmental remediation and wastewater treatment It's a popular phrase used to describe people, things, and ideas that just don't mix—"like oil and water." Except it's not entirely true. Oil and water can mix, and can be very difficult to completely separate when brought together. Think of environmental oil spills or wastewater treatment, and you quickly realize that separating out unwanted oil to restore water to a natural or pure state can be a monumental task. In a research paper published on March 22—the United Nations-designated World Water Day—engineers and physicists from Tufts describe how they devised a low-cost membrane capable of rapidly filtering oil from water and oil ...

PolymPart: Lipid–polymer hybrid nanoparticles (LPHNPs) are next-generation core–shell nanostructures, conceptually derived from both liposome and polymeric nanoparticles (NPs), where a polymer core remains enveloped by a lipid layer. Although they have garnered significant interest, they remain not yet widely exploited or ubiquitous. Recently, a fundamental transformation has occurred in the preparation of LPHNPs, characterized by a transition from a two-step to a one-step strategy, involving synchronous self-assembly of polymers and lipids. Owing to its two-in-one structure, this approach is of particular interest as a combinatorial drug delivery platform in oncology. In particular, the outer surface can be decorated in multifarious ways for active ...